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  • C07D499/00
    		•  Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: [figure], e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring [2] HB CC 4C005
  • C07D499/04
    		•  .Preparation [2] HB CC 4C005
  • C07D499/04@A
    		•  Conversion of the carboxamide radical at the sixth position HB CC 4C005
  • C07D499/04@B
    		•  Alterration of the substitute radical at the a position for the carboxamide radical at the sixth position HB CC 4C005
  • C07D499/04@D
    		•  Introduction of the second substitute radical to the sixth position and conversion HB CC 4C005
  • C07D499/04@E
    		•  modification of the substitute radical at the third position HB CC 4C005
  • C07D499/04@F
    		•  modification of the cyclic sulphur atom at the fourth position HB CC 4C005
  • C07D499/04@Z
    		•  Others HB CC 4C005
  • C07D499/06
    		•  ..Synthesis of the skeleton (by microbiological methods C12P 37/00) [2] HB CC 4C005
  • C07D499/08
    		•  ..Modification of the carboxyl radical, e.g. esterification [2] HB CC 4C005
  • C07D499/10
    		•  ..Modification of the amino radical [2] HB CC 4C005
  • C07D499/10@A
    		•  Formation of a double bond between the nitrogen atom at the sixth position and the carbon atom with a non-penicillin skelton HB CC 4C005
  • C07D499/10@C
    		•  Deacylization HB CC 4C005
  • C07D499/10@D
    		•  .Free-amination HB CC 4C005
  • C07D499/10@Z
    		•  Others HB CC 4C005
  • C07D499/12
    		•  ...Acylation [2] HB CC 4C005
  • C07D499/14
    		•  ..Preparation of salts [2] HB CC 4C005
  • C07D499/16
    		•  ...of alkali or alkaline earth metals [2] HB CC 4C005
  • C07D499/18
    		•  ..Separation; Purification [2] HB CC 4C005
  • C07D499/20
    		•  ...via salts with organic bases [2] HB CC 4C005
  • C07D499/21
    		•  .with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 [6] HB CC 4C005
  • C07D499/21@A
    		•  having a double bond between the nitrogen atom at the sixth position and acyclic carbon atom with a non-penicillin skelton HB CC 4C005
  • C07D499/21@B
    		•  .Second nitrogen atom bonded to the acyclic carbon atom HB CC 4C005
  • C07D499/21@Z
    		•  Others HB CC 4C005
  • C07D499/22
    		•  ..Salts with organic bases; Complexes with organic compounds [2] HB CC 4C005
  • C07D499/24
    		•  ...with acyclic or carbocyclic compounds containing amino radicals [2] HB CC 4C005
  • C07D499/26
    		•  ...with heterocyclic compounds [2] HB CC 4C005
  • C07D499/28
    		•  ..with modified 2-carboxyl group [2] HB CC 4C005
  • C07D499/30
    		•  ...Acid anhydride [2] HB CC 4C005
  • C07D499/32
    		•  ...Esters [2] HB CC 4C005
  • C07D499/34
    		•  ...Thio-acid; Esters thereof [2] HB CC 4C005
  • C07D499/36
    		•  ....O-esters [2] HB CC 4C005
  • C07D499/38
    		•  ....S-esters [2] HB CC 4C005
  • C07D499/40
    		•  ...Amides; Hydrazides; Azides [2] HB CC 4C005
  • C07D499/42
    		•  ..Compounds with a free primary amino radical attached in position 6 [2] HB CC 4C005
  • C07D499/44
    		•  ..Compounds with an amino radical acylated by carboxylic acids, attached in position 6 [2] HB CC 4C005
  • C07D499/46
    		•  ...with acyclic hydrocarbon radicals or such radicals substituted by carbocyclic or heterocyclic rings, attached to the carboxamido radical [2] HB CC 4C005
  • C07D499/48
    		•  ...with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical [2] HB CC 4C005
  • C07D499/50
    		•  ....substituted in beta-position to the carboxamido radical [2] HB CC 4C005
  • C07D499/52
    		•  .....by oxygen or sulfur atoms [2] HB CC 4C005
  • C07D499/54
    		•  .....by nitrogen atoms [2] HB CC 4C005
  • C07D499/56
    		•  .....by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen [2] HB CC 4C005
  • C07D499/58
    		•  ....substituted in alpha-position to the carboxamido radical [2] HB CC 4C005
  • C07D499/60
    		•  .....by oxygen atoms [2] HB CC 4C005
  • C07D499/62
    		•  .....by sulfur atoms [2] HB CC 4C005
  • C07D499/64
    		•  .....by nitrogen atoms [2] HB CC 4C005
  • C07D499/64@A
    		•  having two methyl groups at the third position HB CC 4C005
  • C07D499/64@B
    		•  .having a non-substituted amino group HB CC 4C005
  • C07D499/64@D
    		•  .having an acylized amino group at the a position HB CC 4C005
  • C07D499/64@E
    		•  ..acylized by the carboxylic acid to which the heterocyclic ring is directly bonded or sulphur or nitrogen analogue per se HB CC 4C005
  • C07D499/64@G
    		•  ..having ureide or suphur or nitrogen atom per se HB CC 4C005
  • C07D499/64@H
    		•  ...Ring provided with the nitrogen atom at the end HB CC 4C005
  • C07D499/64@J
    		•  .having the second substitute radical at the sixth position HB CC 4C005
  • C07D499/64@Z
    		•  Others HB CC 4C005
  • C07D499/66
    		•  ......with alicyclic rings as additional substituents on the carbon chain [2] HB CC 4C005
  • C07D499/66@A
    		•  having two methyl groups at the third position HB CC 4C005
  • C07D499/66@B
    		•  .having a non-substituted amino group HB CC 4C005
  • C07D499/66@D
    		•  .having an acylized amino group at the a position HB CC 4C005
  • C07D499/66@E
    		•  ..acylized by the carboxylic acid to which the heterocyclic ring is directly bonded or sulphur or nitrogen analogue per se HB CC 4C005
  • C07D499/66@G
    		•  ..having ureide or suphur or nitrogen atom per se HB CC 4C005
  • C07D499/66@H
    		•  ...Ring provided with the nitrogen atom at the end HB CC 4C005
  • C07D499/66@J
    		•  .having the second substitute radical at the sixth position HB CC 4C005
  • C07D499/66@Z
    		•  Others HB CC 4C005
  • C07D499/68
    		•  ......with aromatic rings as additional substituents on the carbon chain [2] HB CC 4C005
  • C07D499/68@A
    		•  having two methyl groups at the third position HB CC 4C005
  • C07D499/68@B
    		•  .having a non-substituted amino group HB CC 4C005
  • C07D499/68@D
    		•  .having an acylized amino group at the a position HB CC 4C005
  • C07D499/68@E
    		•  ..acylized by the carboxylic acid to which the heterocyclic ring is directly bonded or sulphur or nitrogen analogue per se HB CC 4C005
  • C07D499/68@G
    		•  ..having ureide or suphur or nitrogen atom per se HB CC 4C005
  • C07D499/68@H
    		•  ...Ring provided with the nitrogen atom at the end HB CC 4C005
  • C07D499/68@J
    		•  .having the second substitute radical at the sixth position HB CC 4C005
  • C07D499/68@Z
    		•  Others HB CC 4C005
  • C07D499/70
    		•  ......with hetero rings as additional substituents on the carbon chain [2] HB CC 4C005
  • C07D499/70@A
    		•  having two methyl groups at the third position HB CC 4C005
  • C07D499/70@B
    		•  .having a non-substituted amino group HB CC 4C005
  • C07D499/70@D
    		•  .having an acylized amino group at the a position HB CC 4C005
  • C07D499/70@E
    		•  ..acylized by the carboxylic acid to which the heterocyclic ring is directly bonded or sulphur or nitrogen analogue per se HB CC 4C005
  • C07D499/70@G
    		•  ..having ureide or suphur or nitrogen atom per se HB CC 4C005
  • C07D499/70@H
    		•  ...Ring provided with the nitrogen atom at the end HB CC 4C005
  • C07D499/70@J
    		•  .having the second substitute radical at the sixth position HB CC 4C005
  • C07D499/70@Z
    		•  Others HB CC 4C005
  • C07D499/72
    		•  .....by carbon atoms having three bonds to hetero atoms [2] HB CC 4C005
  • C07D499/74
    		•  ...with carbocyclic rings directly attached to the carboxamido radical [2] HB CC 4C005
  • C07D499/76
    		•  ...with hetero rings directly attached to the carboxamido radical [2] HB CC 4C005
  • C07D499/78
    		•  ..Compounds with an amino radical, acylated by carbonic acid, or by nitrogen or sulfur analogues thereof, attached in position 6 [2] HB CC 4C005
  • C07D499/80
    		•  ..Compounds with a nitrogen-containing hetero ring, attached with the ring nitrogen atom in position 6 [2] HB CC 4C005
  • C07D499/86
    		•  .with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 [5,6] HB CC 4C005
  • C07D499/861
    		•  ..with a hydrocarbon radical or a substituted hydrocarbon radical, directly attached in position 6 [6] HB CC 4C005
  • C07D499/865
    		•  ..with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 6 [6] HB CC 4C005
  • C07D499/87
    		•  .Compounds being unsubstituted in position 3 or with substituents other than only two methyl radicals attached in position 3, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, HB CC 4C005
  • C07D499/88
    		•  .Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 [5,6] HB CC 4C005
  • C07D499/881
    		•  ..with a hydrogen atom or an unsubstituted hydrocarbon radical, attached in position 3 [6] HB CC 4C005
  • C07D499/883
    		•  ..with a substituted hydrocarbon radical attached in position 3 [6] HB CC 4C005
  • C07D499/887
    		•  ..with a hetero atom or a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3 [6] HB CC 4C005
  • C07D499/893
    		•  ..with a hetero ring or a condensed hetero ring system, directly attached in position 3 [6] HB CC 4C005
  • C07D499/897
    		•  .Compounds with substituents other than a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, directly attached in position 2 [6] HB CC 4C005
  • C07D499/90
    		•  .further condensed with carbocyclic rings or carbocyclic rings systems [3] HB CC 4C005
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