Descriptions for C07K and notes/indexes are displayed on this screen.
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PEPTIDES (peptides containing β-lactam rings C07D; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, C07D; ergot alkaloids of the cyclic peptide type C07D 519/02; —single cell proteins, enzymes C12N; genetic engineering processes for obtaining peptides C12N 15/00)[4]
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Note(s)
In this subclass, the following terms or expressions are used with the meanings indicated:[4,6,7]"amino acids" are compounds in which at least one amino group and at least one carboxyl group are bound to the same carbon skeleton and the nitrogen atom of the amino group may form part of a ring;"normal peptide link" is one between an alpha-amino group of an amino acid and the carboxyl group — in position 1 — of another alpha-amino acid;"abnormal peptide link" is a link where at least one of the linked amino acids is not an alpha-amino acid or a link formed by at least one carboxyl or amino group being part of the side chain of an alpha-amino acid;"peptides" are compounds containing at least two amino acid units, which are bound through at least one normal peptide link, including oligopeptides, polypeptides and proteins, where"linear peptides" may comprise rings formed through S—S bridges, or through an hydroxy or a mercapto group of an hydroxy- or a mercapto-amino acid and the carboxyl group of another amino acid (e.g. peptide lactones) but do not comprise rings which are formed only through peptide links;"cyclic peptides" are peptides comprising at least one ring formed only through peptide links; the cyclisation may occur only through normal peptide links or through abnormal peptide links, e.g. through the 4-amino group of 2,4-diamino-butanoic acid. Thus, cyclic compounds in which at least one link in the ring is a non-peptide link are considered as "linear peptides";"depsipeptides" are compounds containing a sequence of at least two alpha-amino acids and at least one alpha-hydroxy carboxylic acid, which are bound through at least one normal peptide link and ester links, derived from the hydroxy carboxylic acids, where"linear depsipeptides" may comprise rings formed through S—S bridges, or through an hydroxy or a mercapto group of an hydroxy-, or mercapto-amino acid and the carboxyl group of another amino- or hydroxy-acid but do not comprise rings formed only through peptide or ester links derived from hydroxy carboxylic acids, e.g. Gly-Ala-Gly—OCH2CO2H and Gly—OCH2CO-Ala-Gly are considered as "linear depsipeptides", but HOCH2CO-Gly-Ala-Gly does not contain an ester link, and is thus a derivative of Gly-Ala-Gly which is covered by C07K 5/08;"cyclic depsipeptides" are peptides containing at least one ring formed only through peptide or ester links — derived from hydroxy carboxylic acids —, e.g. [figure]; "hybrid peptides" are peptides produced through fusion or covalent binding of two or more heterologous peptides. Attention is drawn to Note (3) after class C07, which defines the last place priority rule applied in the range of subclasses C07C-C07K and within these subclasses.Therapeutic activity of compounds is further classified in subclass A61P.When classifying in this subclass, classification is also made in group B01D 15/08 insofar as subject matter of general interest relating to chromatography is concerned.Fragments of peptides or peptides modified by removal or addition of amino acids, by substitution of amino acids by others, or by combination of these modifications are classified as the parent peptides. However, fragments of peptides having only four or less amino acids are also classified in group C07K 5/00.Peptides prepared by chemical processes and having an amino acid sequence derived from naturally occurring peptides are classified with the natural one.Peptides prepared by recombinant DNA technology are not classified according to the host, but according to the original peptide expressed, e.g. HIV peptide expressed in E. coli is classified with HIV peptides.
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Subclass indexes
PEPTIDES | Preparation | 1/00 | of undefined number of amino acids | 2/00 | Having up to 20 amino acids in an undefined or only partially defined sequence | 4/00 | Having up to 20 amino acids in a fully defined sequence | 5/00-9/00 | Depsipeptides having up to 20 amino acids in a fully defined sequence | 11/00 | Having more than 20 amino acids | 14/00 | Immunoglobulins | 16/00 | Carrier-bound or immobilised peptides | 17/00 | Hybrid peptides | 19/00 |
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